I think the hand-stop thought bubble is a glitch of some sort. Pretty much the majroity of my sims in my saves are showing it, including NPC sims. It used to indicate that the sim was about to leave the lot. Now they just seem to spam this thought bubble regardless of what they are doing.
If you think your sim has an illness from Get To Work then simply order some medicine and have your sim drink it. if they are not sick the worst that happens is a short dazed moodlet that can easily be overcome by taking a bath with soaks, eating a harvestable or a good meal, cloudgazing etc.