There are 18 skills. Some we've had before: charisma, cooking, fishing, fitness (athletic), gardening, guitar, handiness, logic, mixology, painting, piano, violin and writing.
These are new: comedy, mischief, programming, rocket science, video gaming.
And there are new features to some of the old familiar skills. Sims can write songs with the guitar, piano, and violin, and get them licensed. And next to the handiness workbench in a picture, I saw a guitar and violin that had to have been built on the bench (think orange crate with strings. Or go to SimsVip and look at the pictures).
Apparently, there are only 8 careers, but each has 2 branches.
Entertainer: Musician/Comedian
Writer: Author/Journalist
Painter: Master of the Real/Patron of the Arts
Secret Agent: Diamond Agent/Villain
Criminal: Boss/Oracle
Astronaut: Space Ranger/Smuggler
Culinary: Chef/Mixologist
Tech Guru: eSport Gamer/Start-up Entrepreneur
Sims can also earn money from gardening, fishing, and collecting and selling things.
I'm excited. It looks like a good mix of old and new. Anyway, use the links in Bri's post to get more info.