I don't have the Door of Life and Death either, but I don't see why a flat-ban on Simulate Genetic Merger would be necessary. As long as the child resulting from that isn't an heir, I don't see why it can't be used. We already allow adoption, the Clone Voucher, and cloning sims using the Science skill from University Life.
Though banning Reincarnation sounds fine to me.
As for Plumbots, I also don't have ITF, but from Carl's guide on the Bot-Making skill, none of the challenges seem to necessitate making Plumbots. If someone who actually has the EP can correct me, please do.