I really do apologize. I have read and reread through these posts and remain confused about one thing. The founders are to be treated like heirs. Now obviously they don't have to max their career and everything before the heir is born. Do they still need to max their career, 3 skill challenges, and opps? Do these need to be noted to keep separate from all 16 other generations? Sorry just remained confused despite all my reading.
Founders for world #1 don't need to max career, skill challenges, or opps. They just need to try for baby no later than week 1 day 4.
If you choose to have your founders max a career, do some skill challenges, do some opps -- then all those will be invalidated for future heirs. So let's say your founder max culinary career, that means none of your future heir can count culinary career as their "unique" max career. Yes you will need to note down what career, skill challenges, and opps that your founder completed -- so none of your heir can do those.
Founders for world #2 will be your heir #4 plus his/her spouse. Heir #4 will already have a max career, skill challenges, and opps done.