I like Mood Manager for my solo sim who is my primary travel sim. I use her so I can discover content in WA, and I've still got a lot to see. I hate dungeon diving with sleep, hunger, bladder, loneliness issues.
I've tried using MM with one spouse of a married couple, but it's more of a hassle to keep 2 sims' moods managed, and it's less fun to play.
So I vote MM only with solo sims.