I play with story progression off constantly. It's the first thing I do when I start a new game. I had an instance where my game just froze. All the ambient sounds were going, night and day passed, but absolutely nothing would happen. I ended up going into that specific file folder and going to a previous save before the glitch, as there will be stories with multiple saves as backups, but they only go so far back (if I remember correctly). I had a ton of CC, I was on Vista at the time, and my computer was total crap. I just attributed all my problems to that. Within a couple months, I just deleted everything sims off my computer and started fresh. That problem never happened again, but I had downloaded an auto-save mod when I reinstalled, as a precautionary measure.