Of the three towns I have (SV, TB, BP), I like SV best. It feels the most comfy and most things are fairly accessible. I'm not a big fan of the swampy feel of TB, so that rules out a lot of the area. BP approaches that Big City vibe, but it's deserted. If I'm in the Big City, I expect a crush of pedestrians and whatnot and they just aren't there in BP (I assume it's because of computer limitations). I'm also not a big fan of the whole club scene or celebrity worship or vampires (yawn), so BP doesn't offer much that appeals to me.
I do wish my SV Sims could go visit, however. Spend a day on a shopping excursion in the Big City or spend time visiting friends in TB.