You can play on more than one computer at a time. It is just when the game starts you have to have the disc in the computer. Once the game is loaded, you can take the disc out and put it in a different computer if you want. Or if you are constantly connected to the internet you do not need a disc at all. See
this post. I am not sure why you are having the problem with autorun. I am not a technophobe but technology does not like me. I am limited in my knowledge. Good luck.
EDIT: I am moving this topic to the technical board. This is a technical issue.