No, you can't on an apartment lot but you can if you bulldoze a venue and change the lot designation. I went in, bulldozed an apartment/lot. When I went to change the designation the message was "restricted to apartment". I then bulldozed the gym and changed the lot to retail. I could then build my own retail store. Trying again, I bulldozed a venue and placed a restaurant. The venues in San Misyuno are very unique, with the exception of the gym but it could be interesting to have the entire town be nothing but apartments, restaurants, shops and bars.