I do aspirations as far as you can, before a career is required. As you get the points, you can get rewards, that will greatly help for other aspirations. The "No Sleep" one seems to be the most effective. I try baking, until it requires me to throw a party. Then, I try painting. No career is required for painting. The musical one makes sense, until it asks you to write a song. Athletic makes sense, as a next step. If you've been keeping up with painting, and your career, up to this point, you will probably have enough wealth, to autocomplete the majority of the "Fabulously Wealthy" one. Try completing that one. If you've been upgrading your house all this time, then Mansion Baron makes sense, as the next step. This should give you enough points, to make your Sim's life a lot more efficient & enjoyable. You might try Gardening, after that. Follow it up to the cowplant phase, unless you happen to have berries on you. The rest? Salt to taste. The others might take some time to complete. Just choose them according to your career, if you like.