Renaissance is max 3 skills, right? This is for a dynasty? If for a dynasty be careful what you wish for. I made my founder a 5 Star Chef since she would be the one cooking ambrosia for all the rest of the generations. I gave her Natural Cook, Bookworm, Charismatic, (really need to make friends!), Angler and Green Thumb. The last two were my downfall. Now as the generations move on, none of them are able to max any of the fishing LTW or Gardening ones. If I had been smart she would have been my Ren Sim because she ultimately supermaxed all those skills. Poor things entire life is spent either in front of a stove or in the garden, mostly in the garden.
So, if this is your founder are you sure you want him/her to be a Ren Sim? If so, I would suggest go with Natural Cook because someone has to cook all that ambrosia for generations! Then pick two other skills others in your generations won't particularly want or won't interfere with others maxing out skills that will be doable for someone who is a cook. Let her learn the fishing skill with a class but don't let her max it. Let her garden and learn either by reading, (Bookworm really does help), or by a class, but again don't let her max it. Have his/her spouse max gardening, painting and sculpting. (You need those museum pictures asap) In the cooking field, and many others, Charismatic is important, or maybe Schmoozer. They need to make friends with the boss and other employees to move up the ladder of success quickly.
Read the guide to see what skills/LTW cross over. Forinstance, an artist has many avenues, and if they max out painting, others coming along won't be able to use LTW that require painting to be maxed. Right now my own dynasty is moving along, but I'm truly concerned that later in the game I may have ruined it for others by taking three skills that could affect other's LTW in the future.