I can't help much with cleaned memory of replicator, but would try to load the saved file without deleting them and check and see if it makes a difference.
About replicating ambrosia - I always leave half cook bowl of ambrosia in the basement or somewhere unreachable on lot, when playing dynasty, and havent seen it spoiled. So at least you could have that same bowl of ambrosia used for replicator over and over again, if not cleaning cache files doesn't help.